Purchase SS-31 Research Peptide

SS-31 (Elamipretide) Research Peptide

SS-31, also known as Elamipretide, is a synthetic mitochondria-targeting tetrapeptide widely studied for its interaction with mitochondrial membranes and cardiolipin. It has become an important research tool in cellular bioenergetics, mitochondrial biology, aging research, and oxidative stress investigations.

Identity & Structural Overview

SS-31 is a cell-permeable tetrapeptide with the amino acid sequence:

D-Arg-dimethylTyr-Lys-Phe-NH₂

Unlike many peptides that act through membrane receptors, SS-31 rapidly localizes to the inner mitochondrial membrane where it selectively associates with cardiolipin, a phospholipid essential for mitochondrial structure and energy production.

Mechanism of Action

Research suggests SS-31 binds to cardiolipin within the inner mitochondrial membrane, helping stabilize mitochondrial architecture and support electron transport chain function in experimental models.

Laboratory studies indicate this interaction may:

• Support mitochondrial bioenergetics

• Improve electron transport efficiency

• Reduce excess reactive oxygen species (ROS) production

• Preserve mitochondrial membrane integrity under cellular stress

These properties have made SS-31 a frequently studied compound in research involving aging, ischemia-reperfusion injury, skeletal muscle physiology, cardiovascular biology, and neurodegenerative disease models.

Research Highlights

Experimental studies have investigated SS-31 for its potential role in:

• Mitochondrial function and energy metabolism

• Oxidative stress research

• Skeletal muscle performance models

• Cardiac tissue research

• Neurological and retinal disease models

• Healthy aging and longevity research

• Cellular resilience during metabolic stress

While preclinical findings have been promising, ongoing research continues to evaluate its mechanisms and potential applications.

Product Specifications

Research Use Only

This product is supplied exclusively for laboratory and scientific research purposes.

Not intended for human consumption, therapeutic use, injection, ingestion, or diagnostic purposes.